Diversity among satellite glial cells in dorsal root ganglia of the rat

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Diversity among satellite glial cells in dorsal root ganglia of the rat.

Peripheral glial cells consist of satellite, enteric glial, and Schwann cells. In dorsal root ganglia, besides pseudo-unipolar neurons, myelinated and nonmyelinated fibers, macrophages, and fibroblasts, satellite cells also constitute the resident components. Information on satellite cells is not abundant; however, they appear to provide mechanical and metabolic support for neurons by forming a...

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It has been generally assumed that the cell body (soma) of a neuron, which contains the nucleus, is mainly responsible for synthesis of macromolecules and has a limited role in cell-to-cell communication. Using sniffer patch recordings, we show here that electrical stimulation of dorsal root ganglion (DRG) neurons elicits robust vesicular ATP release from their somata. The rate of release event...

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Activation of satellite glial cells in lumbar dorsal root ganglia contributes to neuropathic pain after spinal nerve ligation.

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2008

ISSN: 1414-431X,0100-879X

DOI: 10.1590/s0100-879x2008005000051